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KMID : 0367419930360081067
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Journal of Korean Pediatric Society
1993 Volume.36 No. 8 p.1067 ~ p.1072
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Intermittent Central Nervous System Irradiation and Intrathecal Chemotherapy for Recurrent Central Nervous System Leukemia in Children
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방준호
정낙균/최우건/김학기/이경수/양만규
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Abstract
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Between 1986 and 1990, four children with recurrent CNS leukemia who had previous CNS prophylaxis therapy were treated with intermittent central nervous system irradiation and intrathecal chemotherapy (IIIC). There was no isolated CNS recurrence.
One
patient died form bone marrow relapse. Three patients are alive without evidence of disease for 3E3/12 year to 3E6/12 year after the diagnosis of recurrence of CNS leukemia. This experience suggests that IIIC may be an effective treatment for
preventing
the recurrence of CNS leukemia without any serious side effects.
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